Best Dog Flea Medication (Jan 2023 Update)

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Are you looking for the Best Dog Flea Medication? If so, you’ve come to the right place.

Choosing the Best Dog Flea Medication can be difficult as there are so many considerations, such as Adams, Bayer, Boehringer Ingelheim, Hartz, Sergeant’s, VET’S BEST, Zoetis. We have done a lot of research to find the top 20 Best Dog Flea Medication available.

The average cost is $36.27. Sold comparable range in price from a low of $9.99 to a high of $168.41.

Based on the research we did, we think PetArmor Plus Flea, Tick & Lice Treatment, for Dogs, 45-88 lbs – 3 pack, 0.091 fl oz applicators is the best overall. Read on for the rest of the great options and our buying guide, where you can find all the information you need to know before making an informed purchase.

20 Best Dog Flea Medication (20 Sellers)

1. Petarmor Plus Flea, Tick & Lice Treatment, For Dogs, 45-88 Lbs – 3 Pack, 0.091 Fl Oz Applicators

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Specifications:

Units in Package 3
Unit Size 0.091 fl oz applicators
Directions Read entire label before each use. Use only on dogs and puppies over 8 weeks of age. Directions for Use: It is a violation of Federal law to use this product in a manner inconsistent with its labeling. Do not allow children to apply product. To prevent harm to you and your dog, read entire label before each use. Follow all directions and precautionary statements carefully. Do not use on cats, rabbits or animals other than dogs. Do not allow your dog to ingest this product. Do not use on puppies under 8 weeks of age or less than 45 lbs. Use entire contents of tube on each dog. Do not split one tube between dogs. Do not use multiple tubes on one dog. Weigh your dog to be sure you are applying the right dose formulated for the weight of your dog. Separate the treated dog from all other dogs and cats for 24 hours after treatment has been applied. How to Open: Remove product tubes from the package. Separate one tube from the others. Hold the tube with notched end pointing up and away from the face and body. Use scissors to cut off the narrow end at the notches along the line. How to Apply: Invert tube over dog and use open end to part dog's hair. Squeeze tube firmly to apply all of the solution to the dog's skin, as directed below. Do not apply more often than once every 4 weeks. Only for Dogs Weighing 45-88 lbs. Do not apply to dogs weighing less than 45 lbs. Apply one tube (0.091 fl oz)(2.68 ml) as a spot to the dog's back between the shoulder blades. Frequency of Application: Use this product monthly for complete control of flea, tick, and chewing lice infestations. Studies show that this product kills adult fleas for up to three months. Apply monthly if your dog is at high risk for flea reinfestation. Apply monthly to control ticks and chewing lice. This product remains effective even after bathing, water immersion, or exposure to sunlight. Allow treated area to dry thoroughly. Do not reapply for thirty (30) days. Storage and Disposal: Pesticide Storage: Do not remove tube from the pack until ready to use. Store in a cool (below 77 degrees F/25 degrees C), dry place inaccessible to children and pets. Do not refrigerate. Protect from direct sunlight. Container Disposal: If Empty: Non-refillable container. Do not reuse or refill this container. Offer for recycling if available. If Partly Filled: Call your local solid waste agency for disposal instructions. Never place unused product down any indoor or outdoor drain.
Ingredients Active Ingredients: Fipronil (9.80%), (S)-Methoprene (8.80%), Other Ingredient: (81.40%).
Warnings Do not use on cats. Keep out of reach of children. Caution: See back label for additional precautionary statements. Precautionary Statements: Hazards to humans. Caution. Harmful if swallowed. Causes eye irritation. Avoid contact with skin, eyes or clothing. Wash hands thoroughly with soap and water after handling and before eating, drinking, chewing gum, using tobacco or using the toilet. Hazards to Domestic Animals: For external use on dogs only. Individual sensitivities, while rare, may occur after using any pesticide product on dogs. Certain medications can interact with pesticides. Do not treat your dog with more than one pesticide product at a time. Over dosing your dog can result in serious illness and even death. Consult a veterinarian before using on medicated, debilitated, aged, pregnant or nursing dogs. Consult a veterinarian before using on dogs with known organ dysfunction. If your dog is exhibiting signs of and/or is being treated for skin dermatitis, talk to your veterinarian before applying any topical flea and tick control product. First Aid: If Swallowed: Call a poison control center or a doctor immediately for treatment advice. Have person sip a glass of water if able to swallow. Do not induce vomiting unless told to do so by a poison control center or doctor. Do not give anything by mouth to an unconscious person. If in Eyes: Flush eyes with plenty of water. Call a doctor if irritation persists. If on Skin: Wash with plenty of soap and water. Get medical attention if irritation persists. Hot Line Number: Have the product container or label with you when calling a poison control center or doctor, or going for treatment. You may also contact 1-888-908-Tick (8425) for emergency medical treatment information. Side Effects: Monitor your dog after application. Some dogs may experience temporary startle effects when any product is applied. Dogs may experience some temporary irritation at the site of product application such as redness, scratching or other signs of discomfort. If signs of sensitivity occur, bathe your dog with a mild soap and rinse with large amounts of water. If these or other side effects occur, consult your veterinarian or call 1-888-908-Tick (8425). If your dog has an unusual reaction to the initial application, consult a veterinarian before repeating application. The most common signs of incidental ingestion are excessive salivation and foaming at the mouth. If these symptoms occur, immediately feed your dog and continue to monitor your dog for the next 24 hours. Do not use on cats. Keep cats away from treated dogs for 24 hours. If applied to a cat or ingested by a cat, contact your veterinarian.

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2. Frontline Plus Flea, Tick & Lice Killer, For Dogs – 3 Doses

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Units in Package 3
Directions See insert for first aid and precautionary statements. It is a violation of Federal Law to use this product in a manner inconsistent with its labeling. Do not allow children to apply product. To prevent harm to you and your pet, read entire label and enclosed directions before each use. Follow all directions and precautionary statements carefully. Use on dogs only. Do not use on rabbits. Do not use on other animals. To kill fleas, flea eggs & larvae, ticks, and chewing lice apply Frontline Plus for Dogs as follows: To Remove Applicator: Lift and remove the plastic tab to expose foil backing; then peel away the foil. Or use scissors to open. Open applicator. Hold upright with foil side toward you and snap applicator tip. Apply Frontline Plus. Part the dog's hair between the shoulder blades. Place the applicator tip just above the skin and squeeze. Apply entire contents of the applicator in a single spot directly onto the animal's skin. Do not apply on top of the hair coat. Avoid contact with treated area until dry. Frontline Plus is approved for use on all dogs, including breeding, pregnant, and lactating bitches and puppies as young as 8 weeks. Frontline Plus remains effective even after bathing, water immersion, or exposure to sunlight. Frequency of Application: When used monthly, Frontline Plus completely breaks the flea life cycle and controls tick and chewing lice infestations. Do not reapply Frontline Plus for 30 days. Frontline Plus kills adult fleas, flea eggs, and flea larvae for up to three months. Frontline Plus also prevents development of all flea stages for up to three months. Frontline Plus can control fleas for up to three months, however, if there is a high risk of reinfestation or if the pet has fleas which may cause flea allergy dermatitis, a once monthly application may be needed. Frontline Plus kills ticks for at least one month. A once monthly application is recommended where tick control is needed. Frontline Plus kills all life stages of ticks (larva, nymph and adult). Frontline Plus kills ticks that may transmit Lyme disease, Rocky Mountain spotted fever, ehrlichiosis, babesiosis, anaplasmosis and other tick-borne diseases. Frontline Plus kills chewing lice for at least one month. A once monthly application is recommended where chewing lice control is needed. Frontline Plus aids in the control of sarcoptic mange infestations. Multiple monthly treatments are recommended for the elimination of mites.
Ingredients Active Ingredients: Fipronil (9.8%), (S)-Methoprene (8.8%). Inert Ingredients: (81.4%).
Warnings Keep out of reach of children.

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3. Bayer Advantus Large Dogs' Oral Flea Treatment, Soft Chews – 7 Count

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Height 4.25
Length 2.25
Width 2.25
Hazardous Material No

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4. Petarmor Plus Flea And Tick Prevention For Small Dogs, 8 Ct.

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Weight 35 oz

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5. K9 Advantix Ii Extra Large Dog 1 Month Dose

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Active Ingredients % by Weight
Imidacloprid 8.80%
Permethrin* 44.00%
Pyriproxyfen 0.44%
Other Ingredients 46.76%

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6. Simparica Trio Chewable Tablets 44.1-88 Lbs 1 Dose

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7. Petarmor Plus Flea And Tick Treatment For Large Dogs (45-88 Pounds) 6 Count

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8. Frontline Plus Flea & Tick For Dogs 89-132 Lbs, 6 Mo

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9. Bravecto For Dogs – 44-88 Lbs (1 Chew)

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10. Vet's Best Flea + Tick Spot-On For Dogs – 4 Count

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11. Capaction Oral Flea Treatment For Dogs 25+ Lbs 6 Doses

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12. Hartz Ultra Guard Flea & Tick Spray, For Dogs – 16 Fl Oz

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Units in Package 1
Unit Size 16 fl oz
Directions Read entire label before each use. Use only on dogs. It is a violation of Federal law to use this product in a manner inconsistent with its labeling. Shake well before use. 1. Hold bottle upright about 6 inches from pet. 2. Spray lightly until the tips of the pet's hair are moist. Keep spray out of pet's eyes. 3. Rub spray into animal's coat. For longhaired dogs ruffle fur to allow spray to reach skin. 4. After 10 minutes, dry dog with towel. 5. Comb and brush coat. 6. Repeat once a week. 7. If you see a tick, spray it directly. 8. Use on bedding and other areas as needed. Recommended Dosage: Spray 25-30 strokes for a small dog (e.g. Terrier). Spray 30-40 strokes for a medium dog (e.g. Spaniel). Spray 40-70 strokes for a large dog (e.g. Labrador). More spray may be needed for longhaired dogs. Storage and Disposal: Do not contaminate water, food or feed by storage or disposal. Pesticide Storage: Store this product in a cool, dry place that is inaccessible to children. Pesticide Disposal: If Empty: Nonrefillable container. Do not reuse or refill this container. Offer for recycling, if available. If Partly Filled: Call your local solid waste agency for disposal instructions. Never place unused product down any indoor or outdoor drain.
Ingredients Active Ingredients: Tetrachlorvinphos (1.08%). Other Ingredients: (98.92%). Total: (100.00%).
Warnings Keep out of reach of children. Precautionary Statements: Hazards to humans and domestic animals. Causes moderate eye irritation. Avoid contact with eyes or clothing. Wash hands thoroughly with soap and water after handling and before eating, drinking, chewing gum, using tobacco or using the toilet. Do not apply to puppies under 6 weeks old. Consult a veterinarian before using this product on debilitated, aged, or medicated animals. Sensitivity may occur after using any pesticide product for pets. If signs of sensitivity occur, bathe your pet with mild soap and rinse with large amounts of water. If signs continue, consult a veterinarian immediately. Do not use near birds, fish or foodstuffs. If used on pregnant or nursing dogs, do not retreat until the puppies are al least 6 weeks old. Do not use this product simultaneously or within 30 days before or after treatment with or exposure to cholinesterase inhibiting drugs, pesticides or chemicals. However, flea and tick collars may be immediately replaced after use. First Aid: Contains an organophosphate that inhibits cholinesterase. If on Skin or Clothing: Take off contaminated clothing. Rinse skin immediately with plenty of water for 15-20 minutes. Call a Poison Control Center or doctor for treatment advice. If in Eyes: Hold eye open and rinse slowly and gently with water for 15-20 minutes. Remove contact lenses, if present, after the first 5 minutes, then continue rinsing eye. Call a Poison Control Center or doctor for treatment advice. If Swallowed: Call a Poison Control Center or doctor immediately for treatment advice. Have person sip a glass of water if able to swallow. Do not induce vomiting unless told to do so by a Poison Control Center or doctor. Do not give anything by mouth to an unconscious person. Have the product container or label with you when calling a Poison Control Center or doctor, or going for treatment. You may also contact 1-800-275-1414 for emergency medical treatment information. Note to Physicians and Veterinarians: This product contains tetrachlorvinphos (an organophosphate) which is a cholinesterase inhibitor. Cholinergic symptoms may include salvation, miosis, incoordination, muscle fasciculation and/or weakness, vomiting and diarrhea. Atropine is antidotal. 2-PAM may be effective as an adjunct to atropine. cal 1-800-275-1414 or your local Poison Control Center for further information.

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13. K9 Advantix Ii Flea & Tick Treatment For Small Dog 2 Dose

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14. Flea Away Natural Flea, Tick & Mosquito Repellent For Dogs & Cats, 100 Chewable Tablets

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15. Hartz Ultra Guard Pro Flea & Tick Treatment, For Dogs & Puppies, Weighing 61-150 Lbs – 3 Pack, 0.220 Fl Oz Tubes

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Directions It is a violation of Federal law to use this product in a manner consistent with its labeling. Read entire label before each use. Use only on dogs or on puppies 12 weeks of age or older. Do not use on dogs or puppies weighing less than 5 lbs. 1. Remove one applicator tube from the package and hold in an upright position pointed away from your face. 2. Twist dispensing tip clockwise about 1/2 turn while pushing down to break the tube's seal. Do not remove the dispensing tip. 3. Position the dispensing tip on the dog's back between the shoulder blades. Use the dispensing tip of the tube to part the dog's hair so that the product will be applied at skin level. Begin squeezing out the contents of the tube to form a stripe as you move from the shoulder blades along the dog's back to the base of the tail. 4. Repeat every month. Do not bathe your dog 48 hours prior to application. Separate treated dog from other pets for 24 hours after treatment as been applied. Storage and Disposal: Do not contaminate water, food or freed by storage and disposal. Pesticide Storage: Keep this product in its tightly closed original container, when not in use. Store in a cool, dry (preferably locked) area that is inaccessible to children and animals. Pesticide Disposal: Wastes resulting from the use of this product may be disposed of on site or at an approved waste disposal facility. Container Disposal: Non-refillable container. Do not reuse or refill container. If Empty: Offer for recycling, if available. If Partly Filled: Call your local solid waste agency for disposal instructions. Never place unused product down any indoor or outdoor drain.
Ingredients Active Ingredients: Etofenprox (55.0%), Piperonyl Butoxide (PBO) ([Butylcarbityl] [6-Propylpiperonyl] Ether and Related Compounds) (10.0%), N-Octyl Bicycloheptene Dicarboximide (MGK 264) (MGK 264, Insecticide Synergist) (1.0%), Pyriproxyfen (Nylar) (0.5%). Other Ingredients: (33.50%). Total: (100.0%).
Warnings Keep out of reach of children. Do not use on cats. Read entire label before each use. Use only on dogs or on puppies 12 weeks of age or older. Do not use on dogs or puppies weighing less than 5 lbs. Precautionary Statements: Hazard to Humans: Causes moderate eye irritation. Avoid contact with eyes, skin or clothing. Wash thoroughly with soap and water after handling and before eating, drinking, chewing gum or using tobacco. Hazards to Domestic Animals: Do not use on other animals. Do not use on dogs or puppies less than 12 weeks old or weighing less than 5 lbs. Do not use this product on debilitated, aged, medicated, pregnant or nursing animals or on animals known first consulting a veterinarian. Sensitivity such as slight transitory redness of the skin at the site of application, may occur after using any pesticide product for pets. If signs of sensitivity occur, bathe your pet with mild soap, rinse with large amounts of water, and consult a veterinarian immediately. Environmental Hazards: This product is toxic to fish. First Aid: If in Eyes: Hold eye open and rinse slowly and gently with water for 15-20 minutes. Remove contact lenses, if present, after the first 5 minutes, then continue rinsing eye. Call a poison control center or doctor for treatment advice. Hot Line Number: Have the product container or label with you when calling a poison control center, doctor or veterinarian, or going for treatment. For additional information on this pesticide product (including health concerns, medical emergencies or pesticides incidents), you may call 1-800-275-1414.

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16. Vectra 3d (Red) 3pk Flea & Tick Control For Dogs Over 95lbs

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Is Discontinued By Manufacturer No
Package Dimensions 8.5 x 5.39 x 0.94 inches; 2.75 Ounces
Item Package Dimensions L x W x H 8.5 x 5.39 x 0.94 inches
Target Audience Keyword dogs
Age Range Description Puppy

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The product has worked well for Heart for many years and she's never had any unexpected, or any, side effects from it.Thomas H

17. Advantage Ii For Dogs, 21-55 Lbs – 4 Pack

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Weight 3.2 oz

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18. Adams Plus Flea And Tick Dip With Pyrethrin 4 Oz.

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19. Martin's Flea Tick And Mange Dip 1 Pint

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20. Vet's Best Flea And Tick Wipes 50 Count

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