Large Dog Flea Medicine For Sale (Jan 2023 Update)

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Are you looking for the Large Dog Flea Medicine? If so, you’ve come to the right place.

Choosing the Large Dog Flea Medicine can be difficult as there are so many considerations, such as Adams, Bayer, Boehringer Ingelheim, Hartz, SENTRY, Sergeant’s, Zoetis. We have done a lot of research to find the top 20 Large Dog Flea Medicine available.

The average cost is $26.98. Sold comparable range in price from a low of $9.71 to a high of $56.99.

Based on the research we did, we think Bayer Advantus Large Dogs' Flea & Tick Treatment, Soft Chew – 30 count is the best overall. Read on for the rest of the great options and our buying guide, where you can find all the information you need to know before making an informed purchase.

20 Best Selling Large Dog Flea Medicine (20 Sellers)

1. Bayer Advantus Large Dogs' Flea & Tick Treatment, Soft Chew – 30 Count

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Weight 0.25 lb

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2. Frontline Plus Flea & Tick For Dogs, Up To 22 Lbs, 3 Doses

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Units in Package 3
Unit Size 0.023 fl oz applicators
Directions It is a violation of Federal Law to use this product in a manner inconsistent with its labeling. Do not allow children to apply product. To prevent harm to you and your pet read entire label and enclosed directions before each use. Follow all directions and precautionary statements carefully use on dogs only. Do not use on rabbits. Do not use on other animals. To kill fleas, all stages of brown dog ticks, American dog ticks, lone star ticks, and deer ticks (which may carry Lyme disease) and chewing lice, apply to dogs or puppies (8 weeks or older) as follows: Remove applicator from child-resistant package. Hold applicator upright and snap applicator tip away from face and body. Place applicator tip through animal's hair to the skin level between the shoulder blades. Squeeze applicator, applying entire contents in a single spot to the animal's skin. Avoid superficial application to the animal's hair. Only one applicator per treatment is needed. Frontline Plus aids in the control of sarcoptic mange infestations. Multiple monthly treatments are recommended for the elimination of mites. Frontline Plus for Dogs can also be used for the treatment and control of flea, tick and chewing lice infestations on breeding, pregnant and lactating bitches. Frequency of Application: When used monthly, Frontline Plus for Dogs completely breaks the flea life cycle and controls tick and chewing lice infestations. Research demonstrates that Frontline Plus kills adult fleas, flea eggs, and flea larvae for up to three months. Frontline Plus also prevents development of all flea stages for up to three months. Although Frontline Plus can control fleas for up to three months, if there is a high risk of reinfestation or if the pet has fleas which may cause flea allergy dermatitis, a once monthly application may be needed. Frontline Plus kills ticks for at least one month. A once monthly application is recommended where tick control is needed. Frontline Plus kills chewing lice for at least one month. A once monthly application is recommended where chewing lice control is needed. For animal use only.
Ingredients Active Ingredients: Fipronil (9.8%), (S)-Methoprene (8.8%), Inert Ingredients: (81.4%).
Warnings Keep out of reach of children.

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3. K9 Advantix Ii Extra Large Dog 1 Month Dose

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Active Ingredients % by Weight
Imidacloprid 8.80%
Permethrin* 44.00%
Pyriproxyfen 0.44%
Other Ingredients 46.76%

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4. K9 Advantix Ii Flea & Tick Treatment For Large Dogs 21-55 Lbs, 2-Pack

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5. Petarmor Plus Flea And Tick Treatment For Large Dogs (45-88 Pounds) 6 Count

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6. Petarmor Plus Flea And Tick Prevention For Dogs, Dog Flea And Tick Treatment, Waterproof Topical, Fast Acting, Large Dogs (45-88 Lbs), 1 Dose

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7. Advantage Ii For Large Dogs, Red, 4 – Pk.

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Active Ingredient % By Weight
Imidacloprid 9.10%
Pyriproxyfen 0.46%
Other Ingredients 90.44%

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8. Nextstar Flea & Tick Topical For Large Dogs 45-88 Lbs – 3 Ct

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9. Petarmor Flea Treatment, For Dogs, Large – 3 Pack, 0.09 Fl Oz Applicators

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Units in Package 3
Unit Size 0.09 fl oz applicators
Directions Directions for Use: It is a violation of Federal Law to use this product in a manner inconsistent with its labeling. Do not allow children to apply this product. Read entire label before each use. Carefully follow all precautionary statements and applicable use directions. For use on dogs only. do not use on rabbits or other animals. For topical application only. Do not allow your dog to ingest this product. Apply PetArmor For Dogs Only to dogs and puppies aged 8 weeks or older and 23-44 lbs., including on breeding, pregnant, and lactating bitches, as indicated below for control of fleas, ticks (including all stages of American dog ticks, brown dog ticks, deer ticks, and lone star ticks), and chewing lice. How to Apply: 1. Remove product applicator from the package. 2. Separate one applicator from the others. Hold the applicator with notched end pointing up and away from the face and body. Use scissors to cut off the narrow end at the notches along the line. 3. Part the dog's hair and place the tip of the applicator behind the neck and between the shoulders. Ensure that the entire application of this product is contained in a single spot on the dog's skin. Be sure to squeeze the applicator thoroughly so that the entire contents are applied. Do not apply the product superficially to the dog's hair. use only one applicator during each application. Do not touch the area where the application was made until it is dry. PetArmor for Dogs also aids in the control of sarcoptic mange infestations. Frequency of Application: Fleas: According to research studies, adult fleas are killed for up to three months following an application of Fipronil. If, however, your dog or puppy is susceptible to flea allergy dermatitis, or if you believe there is a risk of reinfestation, apply once every month. Ticks: Each application kills ticks for one month or longer. For best control of ticks, apply once every month. Chewing Lice: Each application kills chewing lice for one month or longer. For best control of chewing lice, apply once every month. Do not reapply PetArmor for Dogs for thirty (30) days. Storage and Disposal: Pesticide Storage: Do not remove tube from the pack until ready to use. Store in a cool (below 77 degrees F/25 degrees C) dry place inaccessible to children and pets. Do not refrigerate. Protect from direct sunlight. Container Disposal: if empty: Non-refillable container. Do not reuse or refill this container. Offer for recycling if available. if partly filled: Call your local solid waste agency for disposal instructions. never place unused product down any indoor or outdoor drain.
Ingredients Active Ingredients: Fipronil (9.70%), Other Ingredients (90.30%). Total (100.00%).
Warnings Keep out of reach of children. Caution: See back label for additional precautionary statements. Precautionary Statements: Hazards to humans. Caution. Harmful if swallowed. Cause eye irritation. Avoid contact with skin, eyes or clothing. Washing hands thoroughly with soap and water after handling and before eating, drinking, chewing gum, using tobacco, or using the toilet. Hazards to domestic animals. For external use on dogs only. Individual sensitivities, while rare, may occur after using any pesticide product on dogs. Certain medications can interact with pesticides. Do no treat your dog with more than one pesticide product at a time. Over dosing your dog can result in serious illness and even death. Consult a veterinarian before using on medicated, debilitated, aged, pregnant or nursing dogs. Consult a veterinarian before using on dogs with known organ dysfunction. If your dog is exhibiting signs of and/or is being treated for skin dermatitis, talk to your veterinarian before applying any topical flea and tick control product. First Aid: If Swallowed: Call a poison control center or a doctor immediately for treatment advice. Have person sip a glass of water if able to swallow. Do not induce vomiting unless told to do so by a poison control center or doctor. Do not give anything by mouth to an unconscious person. If In Eyes: Hold eye open and rinse slowly and gently with water for 15-20 minutes. Remove contact lenses, if present, after the first 5 minutes, then continue rinsing eye. Call a poison control center or doctor for treatment advice. If On Skin: Wash with plenty of soap and water. Get medical attention if irritation persists. Hot Line Number: Have the product container or label with you when calling a poison control center or doctor, or going for treatment. You may also contact 1-888-908-Tick (8425) for emergency medical treatment information. Physical or Chemical Hazards Flammable: Keep away from heat and open flame. Side Effects: Monitor your dog after application. Infrequent side effects may include signs of skin irritation such as redness, scratching, or other signs of discomfort. gastrointestinal signs such as vomiting and/or diarrhea have been reported. If these or other side effects occur, consult your veterinarian or FidoPharm at 1-88-908-Tick (8425). Do not use on cats. Keep cats away from treated dogs for 24 hours. If applied to a cat or ingested by a cat, contact your veterinarian.

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10. Capstar Oral Flea Treatment For Large Dogs, Tablets – 6 Count

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Species Body Weight
Dog or Cat 2-25 lbs
Dog 25.1-125 lbs

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11. Vet's Best Flea & Tick Drops For Dogs, Medium

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12. Hartz Ultra Guard Pro Flea & Tick Treatment, For Dogs & Puppies, Weighing 61-150 Lbs – 3 Pack, 0.220 Fl Oz Tubes

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Directions It is a violation of Federal law to use this product in a manner consistent with its labeling. Read entire label before each use. Use only on dogs or on puppies 12 weeks of age or older. Do not use on dogs or puppies weighing less than 5 lbs. 1. Remove one applicator tube from the package and hold in an upright position pointed away from your face. 2. Twist dispensing tip clockwise about 1/2 turn while pushing down to break the tube's seal. Do not remove the dispensing tip. 3. Position the dispensing tip on the dog's back between the shoulder blades. Use the dispensing tip of the tube to part the dog's hair so that the product will be applied at skin level. Begin squeezing out the contents of the tube to form a stripe as you move from the shoulder blades along the dog's back to the base of the tail. 4. Repeat every month. Do not bathe your dog 48 hours prior to application. Separate treated dog from other pets for 24 hours after treatment as been applied. Storage and Disposal: Do not contaminate water, food or freed by storage and disposal. Pesticide Storage: Keep this product in its tightly closed original container, when not in use. Store in a cool, dry (preferably locked) area that is inaccessible to children and animals. Pesticide Disposal: Wastes resulting from the use of this product may be disposed of on site or at an approved waste disposal facility. Container Disposal: Non-refillable container. Do not reuse or refill container. If Empty: Offer for recycling, if available. If Partly Filled: Call your local solid waste agency for disposal instructions. Never place unused product down any indoor or outdoor drain.
Ingredients Active Ingredients: Etofenprox (55.0%), Piperonyl Butoxide (PBO) ([Butylcarbityl] [6-Propylpiperonyl] Ether and Related Compounds) (10.0%), N-Octyl Bicycloheptene Dicarboximide (MGK 264) (MGK 264, Insecticide Synergist) (1.0%), Pyriproxyfen (Nylar) (0.5%). Other Ingredients: (33.50%). Total: (100.0%).
Warnings Keep out of reach of children. Do not use on cats. Read entire label before each use. Use only on dogs or on puppies 12 weeks of age or older. Do not use on dogs or puppies weighing less than 5 lbs. Precautionary Statements: Hazard to Humans: Causes moderate eye irritation. Avoid contact with eyes, skin or clothing. Wash thoroughly with soap and water after handling and before eating, drinking, chewing gum or using tobacco. Hazards to Domestic Animals: Do not use on other animals. Do not use on dogs or puppies less than 12 weeks old or weighing less than 5 lbs. Do not use this product on debilitated, aged, medicated, pregnant or nursing animals or on animals known first consulting a veterinarian. Sensitivity such as slight transitory redness of the skin at the site of application, may occur after using any pesticide product for pets. If signs of sensitivity occur, bathe your pet with mild soap, rinse with large amounts of water, and consult a veterinarian immediately. Environmental Hazards: This product is toxic to fish. First Aid: If in Eyes: Hold eye open and rinse slowly and gently with water for 15-20 minutes. Remove contact lenses, if present, after the first 5 minutes, then continue rinsing eye. Call a poison control center or doctor for treatment advice. Hot Line Number: Have the product container or label with you when calling a poison control center, doctor or veterinarian, or going for treatment. For additional information on this pesticide product (including health concerns, medical emergencies or pesticides incidents), you may call 1-800-275-1414.

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13. Petarmor For Dogs, Flea And Tick Treatment For Large Dogs (45-88 Pounds), Includes 3 Month Supply Of Topical Flea Treatments

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14. Petaction Plus Flea, Tick & Lice Treatment, For Dogs, 6-22 Lbs – 3 Pack, 0.023 Fl Oz Applicators

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Units in Package 3
Unit Size 0.023 fl oz applicators
Directions Use only on dogs and puppies weighing 6-22 lbs and 8 weeks or older. Directions for Use: It is a violation of Federal Law to use this product in a manner inconsistent with its labeling. Do not allow children to apply product. To prevent harm to you and your dog, read the entire label and package insert before each use. Follow all directions and precautionary statements carefully. Use on dogs only. Do not use on rabbits or other animals. Side Effects – See package insert for side effects. Frequency of Application: Fleas: When used monthly, PetAction Plus for Dogs breaks the flea life cycle and controls fleas, flea eggs, and flea larvae for up to three months. Although PetAction Plus for Dogs can control fleas for up to three months, if there is a high risk of re-infestation or if the dog has fleas which may cause flea allergy dermatitis, apply this product once a month. Ticks: PetAction Plus for Dogs kills larva, nymph and adult ticks that may transmit lyme disease, Rocky Mountain Spotted Fever, ehrlichiosis, babesiosis, and anaplasmosis for at least one month. For best control of ticks, apply once every month. Chewing Lice: PetAction Plus for Dogs kills chewing lice for at least one month. For best control of chewing lice, apply once every month. Sarcoptic Mites: Applied once a month, PetAction Plus for Dogs aids in the control of sarcoptic mange mite infestations. Do not reapply PetAction Plus for Dogs for 30 days. Storage and Disposal: Do not contaminate water, food, or feed by storage and disposal. Pesticide Storage: Store unused product in original container only, out of reach of children and animals. Pesticide Disposal: If Partly Filled: Call your local solid waste agency for disposal instructions. Never place unused product down any indoor or outdoor drain. Container Handling: Nonrefillable container. Do not reuse or refill this container. If Empty: Place in trash or offer for recycling if available.
Ingredients Active Ingredients: Fipronil (9.8%), (S)-Methoprene (8.8%). Other Ingredients: (81.4%). Total: (100.0%).
Warnings Keep out of reach of children. Caution: See insert label for first aid and precautionary statements. Do not use on cats. Do Not Use on Cats: Keep cats away from treated dogs for 24 hours. If applied to a cat or ingested by a cat, contact your veterinarian.

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15. Capstar Large Dog Flea Treatment

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Kills or Treats Fleas
Repels or Prevents Flea Eggs, Flea Larvae, Fleas
Breed Size Medium Breeds, Large Breeds
Product Form Chewable Tablet, Tablet

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16. Advantus Oral Flea Soft Chews For Small Dogs, 7.5 Mg – 7 Count

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Height 4.25
Length 2.25
Width 2.25
Hazardous Material No

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17. Petarmor Plus Flea, Tick & Lice Treatment, For Dogs, 45-88 Lbs – 3 Pack, 0.091 Fl Oz Applicators

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Units in Package 3
Unit Size 0.091 fl oz applicators
Directions Read entire label before each use. Use only on dogs and puppies over 8 weeks of age. Directions for Use: It is a violation of Federal law to use this product in a manner inconsistent with its labeling. Do not allow children to apply product. To prevent harm to you and your dog, read entire label before each use. Follow all directions and precautionary statements carefully. Do not use on cats, rabbits or animals other than dogs. Do not allow your dog to ingest this product. Do not use on puppies under 8 weeks of age or less than 45 lbs. Use entire contents of tube on each dog. Do not split one tube between dogs. Do not use multiple tubes on one dog. Weigh your dog to be sure you are applying the right dose formulated for the weight of your dog. Separate the treated dog from all other dogs and cats for 24 hours after treatment has been applied. How to Open: Remove product tubes from the package. Separate one tube from the others. Hold the tube with notched end pointing up and away from the face and body. Use scissors to cut off the narrow end at the notches along the line. How to Apply: Invert tube over dog and use open end to part dog's hair. Squeeze tube firmly to apply all of the solution to the dog's skin, as directed below. Do not apply more often than once every 4 weeks. Only for Dogs Weighing 45-88 lbs. Do not apply to dogs weighing less than 45 lbs. Apply one tube (0.091 fl oz)(2.68 ml) as a spot to the dog's back between the shoulder blades. Frequency of Application: Use this product monthly for complete control of flea, tick, and chewing lice infestations. Studies show that this product kills adult fleas for up to three months. Apply monthly if your dog is at high risk for flea reinfestation. Apply monthly to control ticks and chewing lice. This product remains effective even after bathing, water immersion, or exposure to sunlight. Allow treated area to dry thoroughly. Do not reapply for thirty (30) days. Storage and Disposal: Pesticide Storage: Do not remove tube from the pack until ready to use. Store in a cool (below 77 degrees F/25 degrees C), dry place inaccessible to children and pets. Do not refrigerate. Protect from direct sunlight. Container Disposal: If Empty: Non-refillable container. Do not reuse or refill this container. Offer for recycling if available. If Partly Filled: Call your local solid waste agency for disposal instructions. Never place unused product down any indoor or outdoor drain.
Ingredients Active Ingredients: Fipronil (9.80%), (S)-Methoprene (8.80%), Other Ingredient: (81.40%).
Warnings Do not use on cats. Keep out of reach of children. Caution: See back label for additional precautionary statements. Precautionary Statements: Hazards to humans. Caution. Harmful if swallowed. Causes eye irritation. Avoid contact with skin, eyes or clothing. Wash hands thoroughly with soap and water after handling and before eating, drinking, chewing gum, using tobacco or using the toilet. Hazards to Domestic Animals: For external use on dogs only. Individual sensitivities, while rare, may occur after using any pesticide product on dogs. Certain medications can interact with pesticides. Do not treat your dog with more than one pesticide product at a time. Over dosing your dog can result in serious illness and even death. Consult a veterinarian before using on medicated, debilitated, aged, pregnant or nursing dogs. Consult a veterinarian before using on dogs with known organ dysfunction. If your dog is exhibiting signs of and/or is being treated for skin dermatitis, talk to your veterinarian before applying any topical flea and tick control product. First Aid: If Swallowed: Call a poison control center or a doctor immediately for treatment advice. Have person sip a glass of water if able to swallow. Do not induce vomiting unless told to do so by a poison control center or doctor. Do not give anything by mouth to an unconscious person. If in Eyes: Flush eyes with plenty of water. Call a doctor if irritation persists. If on Skin: Wash with plenty of soap and water. Get medical attention if irritation persists. Hot Line Number: Have the product container or label with you when calling a poison control center or doctor, or going for treatment. You may also contact 1-888-908-Tick (8425) for emergency medical treatment information. Side Effects: Monitor your dog after application. Some dogs may experience temporary startle effects when any product is applied. Dogs may experience some temporary irritation at the site of product application such as redness, scratching or other signs of discomfort. If signs of sensitivity occur, bathe your dog with a mild soap and rinse with large amounts of water. If these or other side effects occur, consult your veterinarian or call 1-888-908-Tick (8425). If your dog has an unusual reaction to the initial application, consult a veterinarian before repeating application. The most common signs of incidental ingestion are excessive salivation and foaming at the mouth. If these symptoms occur, immediately feed your dog and continue to monitor your dog for the next 24 hours. Do not use on cats. Keep cats away from treated dogs for 24 hours. If applied to a cat or ingested by a cat, contact your veterinarian.

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18. Petarmor Plus Flea And Tick Prevention For Dogs, Dog Flea And Tick Treatment, Waterproof Topical, Fast Acting, X-Large Dogs (89-132 Lbs), 1 Dose

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19. Frontline Plus Flea And Tick Treatment For Dogs (Large Dog, 45-88 Pounds, 3 Doses)

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20. Advantage Treatment Spray For Dogs, 15 Oz

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Height 10.25
Length 2.62
Width 2.62
Hazardous Material Yes

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