Best Dog Heartworm Prevention (2025 Update)

PetArmor Plus Flea and Tick Prevention for Dogs is a fast-acting, waterproof topical treatment for large dogs weighing between 45-88 lbs. It works by effectively killing fleas, flea eggs, flea larvae, ticks, and chewing lice up to 30 days after application. PetArmor Plus contains fipronil and (S)-methoprene, the same active ingredients as FRONTLINE Plus for Dogs, providing your pet with trusted, vet-quality formula.

Unlike other flea and tick treatments which may only temporarily suppress flea activity, PetArmor Plus works by breaking the flea life cycle. This helps to prevent re-infestation, ensuring your pet stays safe and healthy. One application of PetArmor Plus provides your pet with long-lasting flea and tick protection for up to 30 days. The package includes three (3) waterproof topical applications, providing your pet with flea protection and control for three (3) months.

PetArmor Plus is easy and convenient to use. Simply part the fur on your dog’s back between the shoulder blades and apply the entire contents of one applicator tube in a single spot. Do not apply more than once every 30 days. For best results, do not bathe your pet 24 hours before or after application. PetArmor Plus is a great way to keep your pet safe and protected from fleas and ticks.

K9 Advantix II Flea and Tick Prevention for Large Dogs (21-55 Pounds) is an effective year-round solution for flea and tick prevention. This product is designed for dogs weighing 21 to 55 pounds and comes with two monthly applications. K9 Advantix II works through contact, killing fleas, ticks and mosquitoes without requiring them to bite your pet. This topical formula is easy to apply and starts working within 12 hours, providing 30 days of protection.

K9 Advantix II is an ideal solution to keep your pet safe from fleas and ticks. It is designed to be effective year-round, ensuring your pet remains protected from parasites. This product is easy to apply, simply apply the topical formula directly onto your pet’s skin for long-lasting protection. K9 Advantix II starts working within 12 hours, killing fleas and ticks before they have a chance to bite your pet. This formula also prevents mosquitoes from biting your pet and keeps them safe from the diseases they may carry.

With K9 Advantix II Flea and Tick Prevention, you can rest assured that your pet is safe from fleas, ticks and mosquitoes. This product is designed for large dogs weighing 21 to 55 pounds and comes with two months of protection. The easy to apply topical formula starts working within 12 hours and provides 30 days of protection. K9 Advantix II is an ideal solution for effective year-round flea and tick treatment.

The TevraPet Activate II Flea and Tick Prevention for Dogs is an easy-to-apply topical drop solution offering fast-acting protection and treatment for extra-large dogs over 55 pounds. Developed and approved by veterinarians, Activate II uses the same active ingredients as K9 Advantix II, including Imidacloprid, Permethrin, and Pyriproxyfen.

When applied to the base of a dog's neck, Activate II starts killing flea eggs and larvae within 12 hours of application, providing continuous protection for 30 days per application. Its waterproof formula allows it to spread across the skin, actively protecting your pet from fleas and ticks.

Because Activate II works to break the flea life cycle, it can help to prevent infestations, protecting your pet from potential flea-borne illnesses. The package includes four doses, providing four months of flea and tick protection for your pet.

TevraPet Activate II is made in the USA to the exacting standards we demand for our own pets. It is safe, fast-acting, and effective, giving pet owners the peace of mind that their pet is protected from fleas and ticks. With TevraPet Activate II, you can protect your dog with confidence.

ZoGuard Plus Flea and Tick Prevention for Dogs (Large – 45-88 lb) is an effective way to protect your pet from fleas and ticks. Using the same amount of active ingredients as the leading brand, ZoGuard Plus provides the same flea and tick control for a much lower cost.

This product kills all stages of the flea life cycle, including eggs, larvae, and adults, providing a comprehensive flea treatment for dogs. It's waterproof, which is great for active dogs, as it will remain effective even after swimming or being exposed to sunlight.

ZoGuard Plus is manufactured in the USA and is EPA registered. It's a high-quality and accessible option for flea and tick prevention for large dogs. It's easy to use and provides long-lasting protection for your pet.

The EPA registration number for ZoGuard Plus for Dogs is 91300-5. To ensure optimal protection, use ZoGuard Plus for Dogs and follow the instructions on the product label. With ZoGuard Plus, you can protect your pet from fleas and ticks while keeping them safe and healthy.

TevraPet Activate II Flea and Tick Prevention is a fast-acting topical drops treatment designed specifically to protect your dog from fleas and ticks. This four-month supply is specifically formulated for large dogs weighing between 21 and 55 lbs.

Activate II uses Imidacloprid, Permethrin, and Pyriproxyfen – the same effective active ingredients found in K9 Advantix II for Dogs. Veterinarians approve this product to repel and kill fleas and ticks on contact, before your dog is exposed to bites and potential flea-borne illnesses.

This product helps stop infestations quickly, using an insect growth regulator (IGR) to start killing flea eggs and larvae within 12-hours of application. It is easy to apply, simply by applying to the base of your dog's neck, and the waterproof solution will travel across the skin, providing continuous protection for 30 days per application.

TevraPet Activate II Flea and Tick Prevention is made in America to the exacting standards we demand for our own pets. We are proud to help you protect your dog with confidence.

Revolution Flea & Tick Chewables are the perfect way to keep your dog safe from fleas, ticks, eggs, larvae, and mosquitoes. These chewable tablets are made with natural ingredients and a delicious bacon flavor, making them an easy and safe option for your pup. The advanced formula contains hemp and garlic, which has a complex healing and preventive effect on your pet's body. Plus, no age limits – these antiflea canine treats can be used monthly for adult dogs and puppies.

Revolution Flea & Tick Chewables provide a great alternative to messy collars, drops, sprays, and shampoos. Simply give your dog one or two chews per day (depending on the weight) and you can keep your pet safe from pests. The recommended serving size is up to 10 lbs for one dose, 10-22 lbs for two chews, 31-60 lbs for three capsules, large 61-90 lbs for four pills, and 90-110 lbs for five tablets.

It's important to note that you should always consult your vet before stopping any medication. But, if you're looking for a natural and safe way to protect your pup from fleas and ticks, Revolution Flea & Tick Chewables can help. This pest control product is made in the USA and is free from GMOs, cellulose, canola, corm, and palm. Plus, your pup will love the delicious bacon flavor in every chew. Keep your pet safe with Revolution Flea & Tick Chewables today.

TevraPet FirstAct Plus Flea and Tick Prevention for Large Dogs 45-88 lbs, 6 Monthly Doses, Topical Drops is a vet-quality formula that is easy to use and provides long-lasting protection against fleas and ticks. Each pack of FirstAct Plus contains six monthly topical applicators that start to kill and control fleas and ticks within 24 hours of application.

This powerful formula uses the same active ingredients as Frontline Plus for Dogs, Fipronil and (S)-methoprene, and provides whole-body protection for up to 30 days after each application. Unlike other flea and tick repellents that only temporarily suppress pest activity, FirstAct Plus kills flea eggs and larvae to stop infestations and break the flea and tick life cycle.

Every dose of FirstAct Plus is produced at our facility in Germany to the exacting standards we demand for our own pets and is rigorously tested for quality and potency. We are committed to providing affordable, veterinarian-quality solutions without sacrificing safety, effectiveness, or reliability.

Every single dose of FirstAct Plus is backed by the TevraPet guarantee, and if you or your dog are unsatisfied for any reason, we offer courteous assistance and a no-questions asked refund. With FirstAct Plus, your dog can spend their time enjoying life both indoors and outdoors without worrying about biting bugs.

TevraPet Activate II Flea and Tick Prevention for Dogs provides an effective, long-lasting solution to protect your pet. This 8-month supply is designed for large dogs between 21 and 55 lbs and offers fast-acting protection that starts killing flea eggs and larvae within 12 hours of application.

The Activate II solution contains the same active ingredients as K9 Advantix II, including Imidacloprid, Permethrin, and Pyriproxyfen. This powerful combination is approved by veterinarians to repel and kill fleas and ticks on contact, before your pet is exposed to any bites or illnesses.

Application is simple, and the waterproof solution provides continuous protection for 30 days. After opening the package, simply apply the topical drops to the base of your dog’s neck. The solution will travel across the skin, providing protection from fleas and ticks for a full month.

TevraPet Activate II is made in America and is designed to meet the exacting standards that we demand for our own pets. Protect your pet with confidence, knowing that you’re giving them the best protection available.

Don’t let fleas and ticks ruin your pet’s health and happiness. With TevraPet Activate II Flea and Tick Prevention for Dogs, your pet can enjoy life without the worry of parasites.

TevraPet Activate II Flea and Tick Prevention for Dogs is a fast acting treatment and control that helps protect your pup from fleas and ticks. This topical drops is made with the same safe, fast acting active ingredients used in Advantix II for Dogs. It actively repels and kills fleas and ticks on contact, preventing potential flea borne illnesses.

The Activate II is easy to apply and starts killing flea eggs and larvae within 12 hours of application. Simply apply the drops to the base of your dog’s neck and the waterproof solution will spread across the skin, providing continuous protection for 30 days.

TevraPet Activate II is proudly made in the USA, and is crafted with the same expectations as we have for our own pets. We know you want the best for your pup, so we guarantee that this product is of the highest quality.

Protect your pup and keep them safe from fleas and ticks with TevraPet Activate II Flea and Tick Prevention for Dogs. This fast acting treatment and control is easy to apply and starts killing flea eggs and larvae within 12 hours. Plus, it’s waterproof, providing continuous protection for 30 days per application.

Trust TevraPet Activate II to provide your pup with the best protection against fleas and ticks. We craft this product with the same high standards that we have for our own pets, so you can trust its quality and safety. Keep your pup safe and happy with TevraPet Activate II.

ZoGuard Plus Flea and Tick Prevention for Dogs is a high-quality, accessible flea and tick prevention product for medium-sized dogs between 23-44 pounds. It is manufactured in the USA and EPA registered. This product is specifically designed to break the flea life cycle by killing all stages of fleas, including eggs, larvae, and adults, and eliminating ticks and lice.

ZoGuard Plus is incredibly effective, delivering the same flea and tick control as the leading brand, but for a lot less. It also provides waterproof protection, remaining effective even after bathing, water immersion, or exposure to sunlight, making it a great choice for active dogs.

The four species of ticks that ZoGuard Plus eliminates includes those that may transmit Lyme disease. It is easy to administer, and pet owners can rest assured knowing that their dog is safe from fleas and ticks. ZoGuard Plus is a reliable and affordable option for flea and tick prevention for medium-sized dogs.