Safe Dog Flea Treatment For Sale (2024 Update)

When you shop through links on our site, we may earn an affiliate commission. This educational content is not intended to be a substitute for professional advice.

Are you looking for the Safe Dog Flea Treatment? If so, you’ve come to the right place.

Choosing the Safe Dog Flea Treatment can be difficult as there are so many considerations, such as Adams, Bayer, Boehringer Ingelheim, Hartz, SENTRY, Sergeant’s, VET’S BEST, Zoetis. We have done a lot of research to find the top 20 Safe Dog Flea Treatment available.

The average cost is $19.86. Sold comparable range in price from a low of $5.76 to a high of $56.99.

Based on the research we did, we think Nexgard 10.1-24 lbs 6 Doses for Pets is the best overall. Read on for the rest of the great options and our buying guide, where you can find all the information you need to know before making an informed purchase.

20 Best Selling Safe Dog Flea Treatment (20 Sellers)

1. Nexgard 10.1-24 Lbs 6 Doses For Pets

Product Details:

Specifications:

Reviews:

2. Advantage Flea & Tick Treatment Spray For Dogs – 8 Oz

Product Details:

Specifications:

Weight 0.5 lb

Reviews:

3. Bayer Advantus Large Dogs' Flea & Tick Treatment, Soft Chew – 30 Count

Product Details:

Specifications:

Weight 0.25 lb

Reviews:

4. K9 Advantix Ii Flea & Tick Treatment For Small Dog 2 Dose

Product Details:

Specifications:

Reviews:

5. Hartz Ultra Guard Dual Action Topical, For Dogs & Puppies, 61 To 150 Lbs – 3 Pack, 0.220 Fl Oz Tubes

Product Details:

Specifications:

Units in Package 3
Unit Size 0.220 fl oz tubes
Directions Directions for Use: It is a violation of Federal law to use this product in a manner inconsistent with its labeling. Important! Read entire label before each use. For use only on dogs or puppies 12 weeks of age or older. Do not use on dogs or puppies weighting less than 61 lbs. Do not allow your dog/puppy to ingest this product. Do not exceed labeled dosage amount for dogs. Do not apply more than one tube per treatment. Do not have contact or allow children to have contact with treated area until completely dry. Do not use on other animals. Do not double-dose or apply more than one applicator to dogs heavier than 150 lbs. 1. Remove one applicator tube from the package and hold in an upright position pointed away from your face. 2. Pull off cap. Turn the cap around and place on top of tube. 3. Simply press cap down to break the seal of the tube. Remove cap carefully. 4. Position the tip of the tube on the dog's back between the shoulder blades. Use the tip of the tube to part the dog's hair so that the product will be applied at skin level. Begin squeezing out the contents of the tube to form a stripe as you move from the shoulder blades along the dog's back to the base of the tail. 5. Repeat every month (Do not bathe your dog 48 hours prior to application). Separate treated dog from other pets for 24 hours after treatment has been applied. Storage and Disposal: Keep this product in its tightly closed original container, when not in use. Store in a cool, dry (preferably locked) area that is inaccessible to children and animals. Pesticide Disposal: Wastes resulting from the use of this product may be disposed of on site or at an approved waste disposal facility. Container Handling: Non-refillable container. Do not use or refill this container. If Empty: Offer for recycling, if available. If Partly Filled: Call your local solid waste agency for disposal instructions. Never place unused product down any indoor or outdoor drain.
Ingredients Active Ingredients: Etofenprox (55.0%), Piperonyl Butoxide (PBO) [(Butylcarbityl) (6-Propylpiperonyl) Ether and Related Compounds] (10.0%), N-Octyl Bicycloheptene Dicarboximide (MGK 264) (MGK 264, Insecticide Synergist Nylar, MGK – Registered Trademarks of McLaughlin Gormley King Company) (1.0%), Pyriproxyfen (Nylar): (0.5%). Other Ingredients: (33.50%). Total: (100.0%).
Warnings Keep out of reach of children. Caution: See back panel for additional precautionary statements. Do not use on cats. Precautionary Statements: Hazards to humans. Caution: Causes moderate eye irritation. Avoid contact with eyes, skin or clothing. Wash hands thoroughly with soap and water after handling and before eating, drinking, chewing gum, using tobacco or using toilet. Hazards to Domestic Animals: Do not use on other animals. Do not use on dogs or puppies less than 12 weeks of age. Do not use on dogs or puppies weighing less than 61 lbs. Do not use this product on debilitated, aged, medicated, pregnant or nursing animals or on animals known to be sensitive to pesticide products without first consulting a veterinarian. Sensitivity, such as slight transitory redness of the skin at the site of application, may occur after using any pesticide product for pets. If signs or sensitivity occur, bathe your pet with mild soap, rinse with large amounts of water, and consult a veterinarian immediately. Environmental Hazards: This product is toxic to fish. First Aid: If in Eyes: Hold eye open and rinse slowly and gently with water for 15-20 minutes. Remove contact lenses, if present, after the first 5 minutes, then continue rinsing eye. Call a poison control center or doctor for treatment advice. Hot Line Number: Have the product container or label with you when calling a poison control center, doctor or veterinarian, or going for treatment. For additional information on this pesticide product (including human and veterinary health concerns, medical emergencies or pesticides incidents), you may call 1-800-275-1414, twenty-four (24) hours per day, seven (7) days per week. Side Effects: Monitor your dog after application. Side effects may include signs of skin irritation such as redness, scratching, or other signs of discomfort. Gastrointestinal signs such as vomiting or diarrhea have also been reported. If these or other side effects occur, consult your veterinarian or call 1-800-275-1414. Do not use on cats. Keep cats away from treated dogs for 24 hours. If applied to or ingested by a cat, contact your veterinarian.

Reviews:

6. Sergeant's Guardian Flea & Tick Topical For Dogs 3 Count

Product Details:

Specifications:

Reviews:

Good price. Good Product.MT
works good and nice small. not too greasy.gary
Item desciption says under 66 lbs but the picture says over 66 lbs. Recieved over but needed under 66 lbs.Marilyn

7. Petarmor Plus Flea And Tick Prevention For Dogs, Dog Flea And Tick Treatment, Waterproof Topical, Fast Acting, Large Dogs (45-88 Lbs), 1 Dose

Product Details:

Specifications:

Reviews:

8. Vet's Best 32 Oz Flea & Tick Home Spray

Product Details:

Specifications:

Weight 2 lb

Reviews:

9. Flea Away Natural Flea, Tick & Mosquito Repellent For Dogs & Cats, 100 Chewable Tablets

Product Details:

Specifications:

Reviews:

10. Hartz Ultra Guard Pro Flea & Tick Treatment, For Dogs & Puppies, Weighing 61-150 Lbs – 3 Pack, 0.220 Fl Oz Tubes

Product Details:

Specifications:

Directions It is a violation of Federal law to use this product in a manner consistent with its labeling. Read entire label before each use. Use only on dogs or on puppies 12 weeks of age or older. Do not use on dogs or puppies weighing less than 5 lbs. 1. Remove one applicator tube from the package and hold in an upright position pointed away from your face. 2. Twist dispensing tip clockwise about 1/2 turn while pushing down to break the tube's seal. Do not remove the dispensing tip. 3. Position the dispensing tip on the dog's back between the shoulder blades. Use the dispensing tip of the tube to part the dog's hair so that the product will be applied at skin level. Begin squeezing out the contents of the tube to form a stripe as you move from the shoulder blades along the dog's back to the base of the tail. 4. Repeat every month. Do not bathe your dog 48 hours prior to application. Separate treated dog from other pets for 24 hours after treatment as been applied. Storage and Disposal: Do not contaminate water, food or freed by storage and disposal. Pesticide Storage: Keep this product in its tightly closed original container, when not in use. Store in a cool, dry (preferably locked) area that is inaccessible to children and animals. Pesticide Disposal: Wastes resulting from the use of this product may be disposed of on site or at an approved waste disposal facility. Container Disposal: Non-refillable container. Do not reuse or refill container. If Empty: Offer for recycling, if available. If Partly Filled: Call your local solid waste agency for disposal instructions. Never place unused product down any indoor or outdoor drain.
Ingredients Active Ingredients: Etofenprox (55.0%), Piperonyl Butoxide (PBO) ([Butylcarbityl] [6-Propylpiperonyl] Ether and Related Compounds) (10.0%), N-Octyl Bicycloheptene Dicarboximide (MGK 264) (MGK 264, Insecticide Synergist) (1.0%), Pyriproxyfen (Nylar) (0.5%). Other Ingredients: (33.50%). Total: (100.0%).
Warnings Keep out of reach of children. Do not use on cats. Read entire label before each use. Use only on dogs or on puppies 12 weeks of age or older. Do not use on dogs or puppies weighing less than 5 lbs. Precautionary Statements: Hazard to Humans: Causes moderate eye irritation. Avoid contact with eyes, skin or clothing. Wash thoroughly with soap and water after handling and before eating, drinking, chewing gum or using tobacco. Hazards to Domestic Animals: Do not use on other animals. Do not use on dogs or puppies less than 12 weeks old or weighing less than 5 lbs. Do not use this product on debilitated, aged, medicated, pregnant or nursing animals or on animals known first consulting a veterinarian. Sensitivity such as slight transitory redness of the skin at the site of application, may occur after using any pesticide product for pets. If signs of sensitivity occur, bathe your pet with mild soap, rinse with large amounts of water, and consult a veterinarian immediately. Environmental Hazards: This product is toxic to fish. First Aid: If in Eyes: Hold eye open and rinse slowly and gently with water for 15-20 minutes. Remove contact lenses, if present, after the first 5 minutes, then continue rinsing eye. Call a poison control center or doctor for treatment advice. Hot Line Number: Have the product container or label with you when calling a poison control center, doctor or veterinarian, or going for treatment. For additional information on this pesticide product (including health concerns, medical emergencies or pesticides incidents), you may call 1-800-275-1414.

Reviews:

11. Vet's Best Flea + Tick Spot-On For Dogs – 4 Count

Product Details:

Specifications:

Reviews:

12. Advantus Oral Flea Soft Chews For Small Dogs, 7.5 Mg – 7 Count

Product Details:

Specifications:

Height 4.25
Length 2.25
Width 2.25
Hazardous Material No

Reviews:

13. Hartz Ultra Guard Dual Action Topical, For Dogs & Puppies, 31 To 60 Lbs – 3 Pack, 0.132 Fl Oz Tubes

Product Details:

Specifications:

Units in Package 3
Unit Size 0.132 fl oz tubes
Directions Directions for Use: It is a violation of Federal law to use this product in a manner inconsistent with its labeling. Important! Read entire label before each use. For use only on dogs or puppies 12 weeks of age or older. Do not use on dogs or puppies weighting less than 31 lbs. Do not allow your dog/puppy to ingest this product. Do not exceed labeled dosage amount for dogs. Do not apply more than one tube per treatment. Do not have contact or allow children to have contact with treated area until completely dry. Do not use on other animals. 1. Remove one applicator tube from the package and hold in an upright position pointed away from your face. 2. Pull off cap. Turn the cap around and place on top of tube. 3. Simply press cap down to break the seal of the tube. Remove cap carefully. 4. Position the tip of the tube on the dog's back between the shoulder blades. Use the tip of the tube to part the dog's hair so that the product will be applied at skin level. Begin squeezing out the contents of the tube to form a stripe as you move from the shoulder blades along the dog's back to the base of the tail. 5. Repeat every month (Do not bathe your dog 48 hours prior to application). Separate treated dog from other pets for 24 hours after treatment has been applied. Storage and Disposal: Keep this product in its tightly closed original container, when not in use. Store in a cool, dry (preferably locked) area that is inaccessible to children and animals. Pesticide Disposal: Wastes resulting from the use of this product may be disposed of on site or at an approved waste disposal facility. Container Handling: Non-refillable container. Do not use or refill this container. If Empty: Offer for recycling, if available. If Partly Filled: Call your local solid waste agency for disposal instructions. Never place unused product down any indoor or outdoor drain.
Ingredients Active Ingredients: Etofenprox (55.0%), Piperonyl Butoxide (PBO) [(Butylcarbityl) (6-Propylpiperonyl) Ether and Related Compounds] (10.0%), N-Octyl Bicycloheptene Dicarboximide (MGK 264) (MGK 264, Insecticide Synergist Nylar, MGK – Registered Trademarks of McLaughlin Gormley King Company) (1.0%), Pyriproxyfen (Nylar): (0.5%). Other Ingredients: (33.50%). Total: (100.0%).
Warnings Keep out of reach of children. Caution: See back panel for additional precautionary statements. Do not use on cats. Precautionary Statements: Hazards to humans. Caution: Causes moderate eye irritation. Avoid contact with eyes, skin or clothing. Wash hands thoroughly with soap and water after handling and before eating, drinking, chewing gum, using tobacco or using toilet. Hazards to Domestic Animals: Do not use on other animals. Do not use on dogs or puppies less than 12 weeks of age. Do not use on dogs or puppies weighing less than 31 lbs. Do not use this product on debilitated, aged, medicated, pregnant or nursing animals or on animals known to be sensitive to pesticide products without first consulting a veterinarian. Sensitivity, such as slight transitory redness of the skin at the site of application, may occur after using any pesticide product for pets. If signs or sensitivity occur, bathe your pet with mild soap, rinse with large amounts of water, and consult a veterinarian immediately. Environmental Hazards: This product is toxic to fish. First Aid: If in Eyes: Hold eye open and rinse slowly and gently with water for 15-20 minutes. Remove contact lenses, if present, after the first 5 minutes, then continue rinsing eye. Call a poison control center or doctor for treatment advice. Hot Line Number: Have the product container or label with you when calling a poison control center, doctor or veterinarian, or going for treatment. For additional information on this pesticide product (including human and veterinary health concerns, medical emergencies or pesticides incidents), you may call 1-800-275-1414, twenty-four (24) hours per day, seven (7) days per week. Side Effects: Monitor your dog after application. Side effects may include signs of skin irritation such as redness, scratching, or other signs of discomfort. Gastrointestinal signs such as vomiting or diarrhea have also been reported. If these or other side effects occur, consult your veterinarian or call 1-800-275-1414. Do not use on cats. Keep cats away from treated dogs for 24 hours. If applied to or ingested by a cat, contact your veterinarian.

Reviews:

14. Knockout E.s. Area Treatment For Dogs By Virbac Animal Health

Product Details:

Specifications:

Container Type Can
Dispenser Type Spray
Volume 16 oz

Reviews:

15. Rapid Flea Killer Dogs 25-125 Lbs, Red Label – 12 Capsules

Product Details:

Reviews:

16. Bravecto 1-Month Chews Small Dog (9.9-22 Lbs) 1 Pk

Product Details:

Specifications:

Reviews:

Great product since I have been using bra Vect oh I have not had no flea problems whatsoever great productKim M

17. Spectrum Hot Shot Flea Killer – 14 Oz Bottle

Product Details:

Specifications:

Reviews:

18. Martin's Flea Tick And Mange Dip 1 Pint

Product Details:

Specifications:

Reviews:

19. Petarmor Plus Flea, Tick & Lice Treatment, For Dogs, 45-88 Lbs – 3 Pack, 0.091 Fl Oz Applicators

Product Details:

Specifications:

Units in Package 3
Unit Size 0.091 fl oz applicators
Directions Read entire label before each use. Use only on dogs and puppies over 8 weeks of age. Directions for Use: It is a violation of Federal law to use this product in a manner inconsistent with its labeling. Do not allow children to apply product. To prevent harm to you and your dog, read entire label before each use. Follow all directions and precautionary statements carefully. Do not use on cats, rabbits or animals other than dogs. Do not allow your dog to ingest this product. Do not use on puppies under 8 weeks of age or less than 45 lbs. Use entire contents of tube on each dog. Do not split one tube between dogs. Do not use multiple tubes on one dog. Weigh your dog to be sure you are applying the right dose formulated for the weight of your dog. Separate the treated dog from all other dogs and cats for 24 hours after treatment has been applied. How to Open: Remove product tubes from the package. Separate one tube from the others. Hold the tube with notched end pointing up and away from the face and body. Use scissors to cut off the narrow end at the notches along the line. How to Apply: Invert tube over dog and use open end to part dog's hair. Squeeze tube firmly to apply all of the solution to the dog's skin, as directed below. Do not apply more often than once every 4 weeks. Only for Dogs Weighing 45-88 lbs. Do not apply to dogs weighing less than 45 lbs. Apply one tube (0.091 fl oz)(2.68 ml) as a spot to the dog's back between the shoulder blades. Frequency of Application: Use this product monthly for complete control of flea, tick, and chewing lice infestations. Studies show that this product kills adult fleas for up to three months. Apply monthly if your dog is at high risk for flea reinfestation. Apply monthly to control ticks and chewing lice. This product remains effective even after bathing, water immersion, or exposure to sunlight. Allow treated area to dry thoroughly. Do not reapply for thirty (30) days. Storage and Disposal: Pesticide Storage: Do not remove tube from the pack until ready to use. Store in a cool (below 77 degrees F/25 degrees C), dry place inaccessible to children and pets. Do not refrigerate. Protect from direct sunlight. Container Disposal: If Empty: Non-refillable container. Do not reuse or refill this container. Offer for recycling if available. If Partly Filled: Call your local solid waste agency for disposal instructions. Never place unused product down any indoor or outdoor drain.
Ingredients Active Ingredients: Fipronil (9.80%), (S)-Methoprene (8.80%), Other Ingredient: (81.40%).
Warnings Do not use on cats. Keep out of reach of children. Caution: See back label for additional precautionary statements. Precautionary Statements: Hazards to humans. Caution. Harmful if swallowed. Causes eye irritation. Avoid contact with skin, eyes or clothing. Wash hands thoroughly with soap and water after handling and before eating, drinking, chewing gum, using tobacco or using the toilet. Hazards to Domestic Animals: For external use on dogs only. Individual sensitivities, while rare, may occur after using any pesticide product on dogs. Certain medications can interact with pesticides. Do not treat your dog with more than one pesticide product at a time. Over dosing your dog can result in serious illness and even death. Consult a veterinarian before using on medicated, debilitated, aged, pregnant or nursing dogs. Consult a veterinarian before using on dogs with known organ dysfunction. If your dog is exhibiting signs of and/or is being treated for skin dermatitis, talk to your veterinarian before applying any topical flea and tick control product. First Aid: If Swallowed: Call a poison control center or a doctor immediately for treatment advice. Have person sip a glass of water if able to swallow. Do not induce vomiting unless told to do so by a poison control center or doctor. Do not give anything by mouth to an unconscious person. If in Eyes: Flush eyes with plenty of water. Call a doctor if irritation persists. If on Skin: Wash with plenty of soap and water. Get medical attention if irritation persists. Hot Line Number: Have the product container or label with you when calling a poison control center or doctor, or going for treatment. You may also contact 1-888-908-Tick (8425) for emergency medical treatment information. Side Effects: Monitor your dog after application. Some dogs may experience temporary startle effects when any product is applied. Dogs may experience some temporary irritation at the site of product application such as redness, scratching or other signs of discomfort. If signs of sensitivity occur, bathe your dog with a mild soap and rinse with large amounts of water. If these or other side effects occur, consult your veterinarian or call 1-888-908-Tick (8425). If your dog has an unusual reaction to the initial application, consult a veterinarian before repeating application. The most common signs of incidental ingestion are excessive salivation and foaming at the mouth. If these symptoms occur, immediately feed your dog and continue to monitor your dog for the next 24 hours. Do not use on cats. Keep cats away from treated dogs for 24 hours. If applied to a cat or ingested by a cat, contact your veterinarian.

Reviews:

20. Petarmor Plus Flea And Tick Treatment For Large Dogs (45-88 Pounds) 6 Count

Product Details:

Reviews: